Article

Presymptomatic plasma biomarkers in autosomal dominant Alzheimer’s disease: sequence and timing

2026-03-31

Abstract excerpt

<h4>Background</h4> Autosomal dominant Alzheimer’s disease (ADAD) serves as a model for presymptomatic biomarker discovery. Characterising the temporal profile of plasma biomarker levels in presymptomatic individuals may enhance understanding of disease pathogenesis, inform future clinical trials, and guide clinical interpretation. <h4>Methods</h4> We evaluated 124 proteins using a NUcleic acid-Linked Immuno-San...

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Literature Corpus work: 1a2db24b-f7da-50f3-a994-bcdcaf9ca50d
DOI: 10.64898/2026.03.30.26349682

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