Article

Inflammatory Signatures in MDS: The Missing Link Between Genetics, Microenvironment and Therapy

2026-06-01

Abstract excerpt

Myelodysplastic syndromes are clonal hematopoietic neoplasms in which ineffective hematopoiesis arises within the context of chronic inflammation and immune dysregulation. Growing evidence indicates that aging-associated inflammaging and inflammation-driven remodeling of the bone marrow microenvironment are not secondary phenomena, but active forces that shape clonal selection, lineage commitment, and disease evol...

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Literature Corpus work: 1a2a6f93-3d80-5dbf-91e1-9f6e2c12397f
DOI: 10.20944/preprints202605.2118.v1

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