Article
SOHO State of the Art Update and Next Questions: Biology and Treatment of Myelodysplastic Syndromes.
Clinical lymphoma, myeloma & leukemia - 1 Oct 2017
Sallman David A, Tanaka Tiffany N, List Alan, Bejar Rafael
Abstract excerpt
Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid neoplasms characterized by clonal hematopoiesis leading to bone marrow dysplasia and cytopenias. Recently, significant advancements have been made in understanding the pathogenic mechanisms of this disease. In particular, how a wide array of somatic mutations can induce a common clinical phenotype has been investigated. Specifically, activation...
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