Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammation in myelodysplastic syndrome pathogenesis.

Seminars in hematology - 1 Dec 2024

Rodriguez-Sevilla Juan Jose, Colla Simona

Abstract excerpt

Inflammation is a key driver of the progression of preleukemic myeloid conditions, such as clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS), to myelodysplastic syndromes (MDS). Inflammation is a critical mediator in the complex interplay of the genetic, epigenetic, and microenvironmental factors contributing to clonal evolution. Under inflammatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clonal Hematopoiesis
Share to ASXL1 gene
Share to DNMT3A gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TET2 gene

Share to Inflammation

Share to Mutation

Share to Myelodysplastic Syndromes

Source

Identifiers

PMID: 39424469
DOI: 10.1053/j.seminhematol.2024.09.005

Genes

ASXL1
DNMT3A
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammation in myelodysplastic syndrome pathogenesis.PMID 39424469Read ↗

Inflammatory Signatures in MDS: The Missing Link Between Genetics, Microenvironment and TherapySemantic proximity Read ↗

Inflammatory Signatures in MDS: The Missing Link Between Genetics, Microenvironment, and Therapy.Semantic proximity Read ↗

Immune Dysregulation and Recurring Mutations in Myelodysplastic Syndromes Pathogenesis.Semantic proximity Read ↗

IL-1β–mediated inflammatory signaling drives ineffective erythropoiesis in early-stage myelodysplastic syndromesSemantic proximity Read ↗

Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDSSemantic proximity Read ↗

Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDSSemantic proximity Read ↗

Epidemiology and Pathogenesis of Myelodysplastic Syndrome.Semantic proximity Read ↗

Clonal hematopoiesis and inflammation: A review of mechanisms and clinical implications.Semantic proximity Read ↗

Chronic myelomonocytic leukemia: molecular pathogenesis and therapeutic innovationsSemantic proximity Read ↗

Genomic landscape of MDS/CMML associated with systemic inflammatory and autoimmune disease.Semantic proximity Read ↗

Clonal hematopoiesis and bone marrow inflammation.Semantic proximity Read ↗

Clonal hematopoiesis and associated diseases: A review of recent findings.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.