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Chronic myelomonocytic leukemia: molecular pathogenesis and therapeutic innovations

17 Oct 2024

Abstract excerpt

Chronic myelomonocytic leukemia (CMML) is an aggressive clonal stem cell disorder categorized among myelodysplastic/ myeloproliferative overlap neoplasms. While sharing features with both myelodysplastic syndromes and myeloproliferative neoplasms, CMML has distinct molecular and clinical profiles. The presence of CMML-specific prognostic models, response criteria, and dedicated clinical trials underscores a...

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PMID: 39415698
DOI: 10.3324/haematol.2024.286061

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