Article

Assessing the variations in breast/ovarian cancer risk for Chinese BRCA1/2 carriers

2020-07-26

Abstract excerpt

<h4>Background</h4> Cancer risks vary in different BRCA1/2 mutations. Previous studies based on Caucasian population have identified regions associated with elevated/reduced risks of breast/ovarian cancers. Since ethnic differences are known to affect BRCA1/2 mutation spectra, we are interested in defining Chinese-specific ovarian/breast cancer cluster regions (OCCR/BCCR) and comparing with previously reported Cau...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1a2a21f5-f02d-55e8-887d-cea3e1ad1fa3
DOI: 10.1101/2020.07.20.20135202

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessing the variations in breast/ovarian cancer risk for Chinese BRCA1/2 carriersDOI 10.1101/2020.07.20.20135202Read

Identification of BRCA1:c.5470_5477del as a Founder Mutation in Chinese Ovarian Cancer PatientsSemantic proximity Read

BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls.Semantic proximity Read

Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients.Semantic proximity Read

Comprehensive analysis of BRCA1 and BRCA2 germline mutations in a large cohort of 5931 Chinese women with breast cancer.Semantic proximity Read

<i>BRCA1</i> and <i>BRCA2</i> mutations in ovarian cancer patients from China: ethnic‐related mutations in <i>BRCA1</i> associated with an increased risk of ovarian cancerSemantic proximity Read

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.Semantic proximity Read

Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing SuggestionsSemantic proximity Read

Germline variants profiling of BRCA1 and BRCA2 in Chinese Hakka breast and ovarian cancer patients.Semantic proximity Read

Ovarian cancer risk of Chinese women with BRCA1/2 germline pathogenic variantsSemantic proximity Read

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individualsSemantic proximity Read

The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.Semantic proximity Read

Prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from Yunnan Province in southwest China.Semantic proximity Read