Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients.

Oncotarget - 23 Feb 2016

Kim Yeong C, Zhao Linli, Zhang Hanwen, Huang Ye, Cui Jian, Xiao Fengxia, Downs Bradley, Wang San Ming

Abstract excerpt

Germline mutations in BRCA1 and BRCA2 are the most penetrating genetic predispositions for breast and ovarian cancer, and their presence is largely ethnic-specific. Comprehensive information about the prevalence and spectrum of BRCA mutations has been collected in European and North American populations. However, similar information is lacking in other populations, including the mainland Chinese population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Breast Neoplasms

Share to Gene Frequency

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26848529
DOI: 10.18632/oncotarget.7144
PMCID: PMC4891063

Genes

BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients.PMID 26848529Read ↗

Germline variants profiling of BRCA1 and BRCA2 in Chinese Hakka breast and ovarian cancer patients.Semantic proximity Read ↗

Prevalence of BRCA1/BRCA2 pathogenic variation in Chinese Han population.Semantic proximity Read ↗

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.Semantic proximity Read ↗

Comprehensive analysis of BRCA1 and BRCA2 germline mutations in a large cohort of 5931 Chinese women with breast cancer.Semantic proximity Read ↗

Assessing the variations in breast/ovarian cancer risk for Chinese BRCA1/2 carriersSemantic proximity Read ↗

Germline variant spectrum of hereditary cancer susceptibility genes in a Chinese cohort.Semantic proximity Read ↗

BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls.Semantic proximity Read ↗

Prevalence and Spectrum of BRCA1/2 Germline Mutations in Women with Breast Cancer in China Based on Next-Generation Sequencing.Semantic proximity Read ↗

The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.Semantic proximity Read ↗

Comprehensive profiling of BRCA1 and BRCA2 variants in breast and ovarian cancer in Chinese patients.Semantic proximity Read ↗

Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer.Semantic proximity Read ↗

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individualsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.