Article

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

2019-01-09

Abstract excerpt

To determine the prevalence and clinical prediction factors associated with deleterious mutations among 882 high-risk Chinese individuals who underwent multigene panel testing for hereditary breast and ovarian cancer (HBOC) risk assessment. Subjects were selected from individuals referred for genetic testing using a 21-gene panel (Oseq-BRCA) between January 2015 and March 2018. The distribution and prevalence of d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02fa8c25-8c63-576e-9748-0db93f289c4b
DOI: 10.1101/514539

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individualsDOI 10.1101/514539Read

Prevalence of hereditary breast and ovarian cancer (HBOC) predisposition gene mutations among 882 HBOC high-risk Chinese individuals.Semantic proximity Read

Multigene germline testing for epithelial ovarian cancer in China.Semantic proximity Read

Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test.Semantic proximity Read

Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer.Semantic proximity Read

BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls.Semantic proximity Read

Germline mutations in Chinese ovarian cancer with or without breast cancer.Semantic proximity Read

Germline variant spectrum of hereditary cancer susceptibility genes in a Chinese cohort.Semantic proximity Read

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.Semantic proximity Read

Germline Mutation in 1338 BRCA-Negative Chinese Hereditary Breast and/or Ovarian Cancer Patients: Clinical Testing with a Multigene Test Panel.Semantic proximity Read

Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing SuggestionsSemantic proximity Read

Prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from Yunnan Province in southwest China.Semantic proximity Read

The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels.Semantic proximity Read