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Article

BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls.

Gynecologic oncology - 1 Oct 2018

Li Ang, Xie Rong, Zhi Qihuan, Deng Yixiao, Wu Yangming, Li Weiwei, Yang Lu, Jiao Zinan, Luo Jiaqi, Zi Yi, Sun Gang, Zhang Jiajia, Shi Yujian, Liu Jian

Abstract excerpt

OBJECTIVE: To investigate the BRCA status in Chinese patients with ovarian cancer (OC). Though there were two large prevalence studies in Chinese OC patients, this was the first time to observe it in healthy controls. METHODS: We performed BRCA mutation screening using next-generation sequencing to determine the prevalence of BRCA germline deleterious mutations in an unselected cohort of Chinese OC patients...

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Identifiers

PMID: 30078507
DOI: 10.1016/j.ygyno.2018.07.024

Genes

BRCA1
BRCA2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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