Article

CiDRE <sup> </sup> M2c Macrophages Hijacked by SARS-CoV-2 Cause COVID-19 Severity

2022-11-23

Abstract excerpt

Infection of the lungs with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via the angiotensin I converting enzyme 2 (ACE2) receptor induces a cytokine storm. However, the precise mechanisms involved in severe coronavirus disease 2019 (COVID-19) pneumonia are unknown. Here, we show that interleukin-10 (IL-10) changed normal alveolar macrophages into ACE2-expressing M2c-type macrophages that functione...

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Literature Corpus work: 1a1830a9-e925-5c3a-b991-cd60453fe44d
DOI: 10.2139/ssrn.4281074

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