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Article

SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19

2 Feb 2022

Abstract excerpt

The review aims to consolidate research findings on the molecular mechanisms and virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and their relevance to four typical stages in the development of acute viral infection. These four stages are invasion; primary blockade of antiviral innate immunity; engagement...

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PMID: 35163638
DOI: 10.3390/ijms23031716

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