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Article

Hard CiDRE revs up macrophage infectivity in COVID-19.

Immunity - 8 Aug 2023

Bhattacharya Mallar

Abstract excerpt

IL-10 has been linked to COVID-19 severity, but whether it is causal is unclear. In this issue of Immunity, Mitsui et al. find that a specific single-nucleotide polymorphism (SNP) results in expression of an IL10RB-IFNAR2 fusion protein that intensifies IL-10-mediated induction of ACE2 expression and viral infectivity of macrophages.

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Identifiers

PMID: 37557078
DOI: 10.1016/j.immuni.2023.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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