Article

CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses

2022-03-29

Abstract excerpt

Exacerbated and persistent innate immune response marked by pro-inflammatory cytokine expression is thought to be a major driver of chronic COVID-19 pathology. Although macrophages are not the primary target cells of SARS-CoV-2 infection in humans, viral RNA and antigens in activated monocytes and macrophages have been detected in post-mortem samples, and dysfunctional monocytes and macrophages have been hypothesi...

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Literature Corpus work: 33acee15-bb9b-58f0-9a00-905143810b00
DOI: 10.1101/2022.03.29.486190

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