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Article

Therapeutic face of RNAi:<i>in vivo</i>challenges

15 Nov 2014

Abstract excerpt

INTRODUCTION: RNA interference is a sequence-specific gene silencing phenomenon in which small interfering RNAs (siRNAs) can trigger gene transcriptional and post-transcriptional silencing. This phenomenon represents an emerging therapeutic approach for in vivo studies by efficient delivery of specific synthetic siRNAs against diseases. Therefore, simultaneous development of synthetic siRNAs along with novel...

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PMID: 25399911
DOI: 10.1517/14712598.2015.983070

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