Article

Erythrocyte CD55 facilitates the internalization of <i>Plasmodium falciparum</i> parasites

2020-07-27

Abstract excerpt

Invasion of human erythrocytes by the malaria parasite Plasmodium falciparum is a multi-step process. Previously, a forward genetic screen for P. falciparum host factors identified erythrocyte CD55 as essential for invasion, but its specific role and how it interfaces with the other factors that mediate this complex process are unknown. Using CRISPR-Cas9 editing, antibody-based inhibition, and live cell imaging,...

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Literature Corpus work: 19e774d0-66d6-55f1-a250-6a68ca30886a
DOI: 10.1101/2020.07.27.223644

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