Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion

13 Oct 2023

Abstract excerpt

The malaria parasite Plasmodium falciparum invades and replicates asexually within human erythrocytes. CD44 expressed on erythrocytes was previously identified as an important host factor for P falciparum infection through a forward genetic screen, but little is known about its regulation or function in these cells, nor how it may be used by the parasite. We found that CD44 can be efficiently deleted from primary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to HIV Research and Treatment
Share to Malaria Research and Control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37832027
DOI: 10.1182/blood.2023020831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasionPMID 37832027Read ↗

<i>Plasmodium falciparum</i> exploits CD44 as a co-receptor for erythrocyte invasionSemantic proximity Read ↗

CD44 cross-linking promotes <i>Plasmodium falciparum</i> invasionSemantic proximity Read ↗

Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human ErythrocytesSemantic proximity Read ↗

Erythrocyte CD55 facilitates the internalization of <i>Plasmodium falciparum</i> parasitesSemantic proximity Read ↗

A forward genetic screen identifies erythrocyte CD55 as essential for <i>Plasmodium falciparum</i> invasionSemantic proximity Read ↗

The cytoplasmic domain of the Plasmodium falciparum ligand EBA-175 is essential for invasion but not protein trafficking.Semantic proximity Read ↗

Generation of an immortalized erythroid progenitor cell line from peripheral blood: A model system for the functional analysis of Plasmodium spp. invasionSemantic proximity Read ↗

Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirementsSemantic proximity Read ↗

Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial interventionSemantic proximity Read ↗

Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasitesSemantic proximity Read ↗

In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria InfectionSemantic proximity Read ↗

Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.