Article

Co-transcriptional splicing regulates 3’ end cleavage during mammalian erythropoiesis

2020-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Pre-mRNA processing steps are tightly coordinated with transcription in many organisms. To determine how co-transcriptional splicing is integrated with transcription elongation and 3’ end formation in mammalian cells, we performed long-read sequencing of individual nascent RNAs and PRO-seq during mouse erythropoiesis. Splicing was not accompanied by transcriptional pausing and was detected when...

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Literature Corpus work: 19baf633-5286-5522-a807-1231e6c73109
DOI: 10.1101/2020.02.11.944595

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