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An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer’s Disease

2023-06-08

Abstract excerpt

<h4>Background</h4> The X chromosome is often omitted in disease association studies despite containing thousands of genes which may provide insight into well-known sex differences in the risk of Alzheimer’s Disease. <h4>Objective</h4> To model the expression of X chromosome genes and evaluate their impact on Alzheimer’s Disease risk in a sex-stratified manner. <h4>Methods</h4> Using elastic net, we evaluated m...

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Literature Corpus work
190f5502-3043-5121-8cb6-89071b3b50be
DOI
10.1101/2023.06.06.543877
Open publication

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An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer’s DiseaseDOI 10.1101/2023.06.06.543877
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