X-Chromosome-wide association study for Alzheimer’s disease

Abstract excerpt

Due to methodological reasons, the X-chromosome has not been featured in the major genome-wide association studies on Alzheimer’s Disease (AD). To finally address this and better characterize the genetic landscape of AD, we performed an in-depth X-Chromosome-Wide Association Study (XWAS) in 115,841 AD cases or AD proxy cases, including 52,214 clinically-diagnosed AD cases, and 613,671 controls. We considered three...

Topics

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• Aged, 80 and over
• Aged
• Alzheimer Disease
• Case-Control Studies
• Chromosomes, Human, X
• Genome-Wide Association Study
• Polymorphism, Single Nucleotide
• X Chromosome Inactivation

Identifiers and source

Literature Corpus work

ee4acbf5-47da-5dea-aff2-cb5286dd856b

DOI

10.1101/2024.05.02.24306739