Article

RNA editing is a molecular clock in unmodified human cells

2024-11-19

Abstract excerpt

Despite major advances in spatial RNA sequencing, the ability to extract temporal information in RNA sequencing experiments is still limited. Here, we describe Transcriptome Timestamping (T2), a system which harnesses naturally occurring A-to-I editing of RNA transcripts in unmodified human cells to infer transcriptional history. T2 provides age estimates for individual RNA transcripts, and serves as an endogenous...

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Identifiers and source

Literature Corpus work: 18e80465-e79b-571b-811e-84c49278aa44
DOI: 10.1101/2024.11.18.624170

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