Article

Whole-genome single-cell multimodal history tracing to reveal cell identity transition

2025-08-15

Abstract excerpt

<h4>ABSTRACT</h4> Advances in single-cell sequencing have deepened our understanding of cellular identities. However, because they inherently capture only static snapshots, after which no further observations are possible, we cannot compare past and present profiles within the same cell. Thus, multi-time-point whole-genome profiling at single-cell resolution has been a long-standing goal. Here, we introduce the H...

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Literature Corpus work: 7c85a25b-6b05-5ecf-adea-c3f785b69c03
DOI: 10.1101/2025.08.12.669973

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