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A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes

2023-01-27

Abstract excerpt

Molnupiravir, an antiviral medication that has been widely used against SARS-CoV-2, acts by inducing mutations in the virus genome during replication. Most random mutations are likely to be deleterious to the virus, and many will be lethal, and so molnupiravir-induced elevated mutation rates reduce viral load 2,3 . However, if some patients treated with molnupiravir do not fully clear SARS-CoV-2 infections, there...

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Literature Corpus work
18df586e-ed7e-595a-98a6-c6efadec929b
DOI
10.1101/2023.01.26.23284998
Open publication

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A molnupiravir-associated mutational signature in global SARS-CoV-2 genomesDOI 10.1101/2023.01.26.23284998
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