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Article

Mutational spectrum of SARS-CoV-2 during the global pandemic.

Experimental & molecular medicine - 1 Aug 2021

Yi Kijong, Kim Su Yeon, Bleazard Thomas, Kim Taewoo, Youk Jeonghwan, Ju Young Seok

Abstract excerpt

Viruses accumulate mutations under the influence of natural selection and host-virus interactions. Through a systematic comparison of 351,525 full viral genome sequences collected during the recent COVID-19 pandemic, we reveal the spectrum of SARS-CoV-2 mutations. Unlike those of other viruses, the mutational spectrum of SARS-CoV-2 exhibits extreme asymmetry, with a much higher rate of C>U than U>C substitutions,...

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Identifiers

PMID: 34453107
DOI: 10.1038/s12276-021-00658-z
PMCID: PMC8393781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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