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Phosphate is the third nutrient monitored by TOR in <i>Candida albicans</i> and provides a target for fungal-specific indirect TOR inhibition

2017-05-27

Abstract excerpt

The TOR pathway regulates morphogenesis and responses to host cells in the fungal pathogen Candida albicans . Eukaryotic TOR complex 1 (TORC1) induces growth and proliferation in response to nitrogen and carbon source availability. Our unbiased genetic approach seeking new components of TORC1 signaling in C. albicans revealed that the phosphate transporter Pho84 is required for normal TORC1 activity. We found th...

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Identifiers and source

Literature Corpus work
18bd7069-d672-500e-8050-82f2748ebc17
DOI
10.1101/142745
Open publication

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Phosphate is the third nutrient monitored by TOR in <i>Candida albicans</i> and provides a target for fungal-specific indirect TOR inhibitionDOI 10.1101/142745
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