Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence

30 Jul 2018

Abstract excerpt

Phosphate is an essential macronutrient required for cell growth and division. Pho84 is the major high-affinity cell-surface phosphate importer of Saccharomyces cerevisiae and a crucial element in the phosphate homeostatic system of this model yeast. We found that loss of Candida albicans Pho84 attenuated virulence in Drosophila and murine oropharyngeal and disseminated models of invasive infection, and conferred...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Pneumocystis jirovecii pneumonia detection and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30059535
DOI: 10.1371/journal.ppat.1007076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulencePMID 30059535Read ↗

Phosphate is the third nutrient monitored by TOR in <i>Candida albicans</i> and provides a target for fungal-specific indirect TOR inhibitionSemantic proximity Read ↗

<i>Candida albicans’</i> inorganic phosphate transport and evolutionary adaptation to phosphate scarcitySemantic proximity Read ↗

Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity.Semantic proximity Read ↗

Transcriptional profiling reveals the role of Candida albicans Rap1 in oxidative stress responseSemantic proximity Read ↗

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.Semantic proximity Read ↗

Glycerophosphocholine provision rescues Candida albicans growth and signaling phenotypes associated with phosphate limitation.Semantic proximity Read ↗

The PHO pathway regulates white-opaque switching and sexual mating in the human fungal pathogen Candida albicans.Semantic proximity Read ↗

Yippee-like protein Moh1 links gene expression to metabolism and selective stress resistance in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Phosphate transport and sensing in Saccharomyces cerevisiae.Semantic proximity Read ↗

Magnesium deprivation affects cellular circuitry involved in drug resistance and virulence in Candida albicansSemantic proximity Read ↗

Participation of Zip3, a ZIP domain-containing protein, in stress response and virulence in Cryptococcus gattii.Semantic proximity Read ↗

The Candida albicans Pho4 Transcription Factor Mediates Susceptibility to Stress and Influences Fitness in a Mouse Commensalism ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.