Article
Glycerophosphocholine provision rescues Candida albicans growth and signaling phenotypes associated with phosphate limitation.
mSphere - 20 Dec 2023
King William R, Acosta-Zaldívar Maikel, Qi Wanjun, Cherico Nicholas, Cooke Lauren, Köhler Julia R, Patton-Vogt Jana
Abstract excerpt
IMPORTANCE: Candida albicans is the most commonly isolated species from patients suffering from invasive fungal disease. C. albicans is most commonly a commensal organism colonizing a variety of niches in the human host. The fungus must compete for resources with the host flora to acquire essential nutrients such as phosphate. Phosphate acquisition and homeostasis have been shown to play a key role in C. albicans...
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