Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.

Proceedings of the National Academy of Sciences of the United States of America - 13 Jun 2017

Liu Ning-Ning, Flanagan Peter R, Zeng Jumei, Jani Niketa M, Cardenas Maria E, Moran Gary P, Köhler Julia R

Abstract excerpt

The Target of Rapamycin (TOR) pathway regulates morphogenesis and responses to host cells in the fungal pathogen Candida albicans Eukaryotic Target of Rapamycin complex 1 (TORC1) induces growth and proliferation in response to nitrogen and carbon source availability. Our unbiased genetic approach seeking unknown components of TORC1 signaling in C. albicans revealed that the phosphate transporter Pho84 is required...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Candida albicans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Hyphae

Share to Mechanistic Target of Rapamycin Complex 1

Share to Monomeric GTP-Binding Proteins

Share to Phosphates

Share to Regulon

Source

Open in PubMed Open full text

Identifiers

PMID: 28566496
DOI: 10.1073/pnas.1617799114
PMCID: PMC5474788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.PMID 28566496Read ↗

Phosphate is the third nutrient monitored by TOR in <i>Candida albicans</i> and provides a target for fungal-specific indirect TOR inhibitionSemantic proximity Read ↗

The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm FormationSemantic proximity Read ↗

Target of Rapamycin (TOR) in Nutrient Signaling and Growth ControlSemantic proximity Read ↗

<i>Candida albicans’</i> inorganic phosphate transport and evolutionary adaptation to phosphate scarcitySemantic proximity Read ↗

Glycerophosphocholine provision rescues Candida albicans growth and signaling phenotypes associated with phosphate limitation.Semantic proximity Read ↗

Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity.Semantic proximity Read ↗

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulenceSemantic proximity Read ↗

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read ↗

The Regulatory Proteins Rtg1/3 Govern Sphingolipid Homeostasis in the Human-Associated Yeast Candida albicans.Semantic proximity Read ↗

Stress- and metabolic responses of <i>Candida albicans</i> require Tor1 kinase N-terminal HEAT repeatsSemantic proximity Read ↗

Mds3 regulates morphogenesis in Candida albicans through the TOR pathway.Semantic proximity Read ↗

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chipsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.