Article

WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers

2022-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Wnt ligand WNT4 is critical in female reproductive tissue development, with WNT4 dysregulation linked to related pathologies including breast cancer (invasive lobular carcinoma, ILC) and gynecologic cancers. WNT4 signaling in these contexts is distinct from canonical Wnt signaling yet inadequately understood. We previously identified atypical intracellular activity of WNT4 (independent of Wnt se...

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Literature Corpus work: 18bb2ddd-7257-5d80-adb5-75444cc09f65
DOI: 10.1101/2022.07.15.499747

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