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The role of LSM1 in breast cancer: Shaping metabolism and tumor-associated macrophage infiltration

22 Nov 2023

Abstract excerpt

LSM1 is part of the cytoplasmic protein complex Lsm1-7-Pat1 and is likely involved in pre-mRNA degradation by aiding U4/U6 snRNP formation. More research is needed to uncover LSM1's potential in breast cancer (BRCA) clinical pathology, the tumor immune microenvironment, and precision oncology. We discovered LSM1 as a diagnostic marker for advanced BRCA with poor survival, using a multi-omics approach. We studied...

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PMID: 37995895
DOI: 10.1016/j.phrs.2023.107008

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