Article

Complementary Omics Strategies to Dissect p53 Signaling Networks Under Nutrient Stress

2022-01-12

Abstract excerpt

<title>Abstract</title> <p>Signaling trough p53 is a major cellular stress response mechanism and increases upon nutrient stresses such as starvation. Here, we show in a human hepatoma cell line that starvation leads to robust nuclear p53 stabilization. Using BioID, we determine the cytoplasmic p53 interaction network within the immediate-early starvation response and show that p53 is dissociated from several met...

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Literature Corpus work: 18647206-e0cf-565f-8520-ad1d979618cc
DOI: 10.21203/rs.3.rs-1224764/v1

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