Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer

18 Oct 2019

Abstract excerpt

BACKGROUND: The TP53 gene is one of the most commonly inactivated tumor suppressors in human cancers. p53 functions during cancer progression have been linked to a variety of transcriptional and non-transcriptional activities that lead to the tight control of cell proliferation, senescence, DNA repair, and cell death. However, converging evidence indicates that p53 also plays a major role in metabolism in both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Cancer-related Molecular Pathways
Share to Metabolism, Diabetes, and Cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31685430
DOI: 10.1016/j.molmet.2019.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancerPMID 31685430Read ↗

Control of metabolism by p53 – Cancer and beyondSemantic proximity Read ↗

The role of tumor suppressor p53 in metabolism and energy regulation, and its implication in cancer and lifestyle-related diseasesSemantic proximity Read ↗

The crisscross between p53 and metabolism in cancer.Semantic proximity Read ↗

Taking up the reins of power: metabolic functions of p53Semantic proximity Read ↗

Regulation of Metabolic Activity by p53Semantic proximity Read ↗

Tumor suppressor p53 and its mutants in cancer metabolism.Semantic proximity Read ↗

Mechanistic roles of mutant p53 governing lipid metabolism.Semantic proximity Read ↗

The role of the p53 tumor suppressor in metabolism and diabetes.Semantic proximity Read ↗

Emerging Roles of p53 Family Members in Glucose Metabolism.Semantic proximity Read ↗

Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer diseaseSemantic proximity Read ↗

Exploring the multiple roles of guardian of the genome: P53Semantic proximity Read ↗

The p53 Tumor Suppressor in the Control of Metabolism and FerroptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.