Article

RBP4-BACH1 Interaction Modulates Transcriptional Regulation of Insulin Signaling Pathway Genes

2026-08-27

Abstract excerpt

Retinol-binding protein 4 (RBP4) exhibits diurnal oscillatory pattern and is elevated under conditions of circadian disruption and in type 2 diabetes mellitus, yet the molecular link between RBP4 and impaired glucose metabolism remains elusive. Here, we overexpressed RBP4 in human hepatoma Huh7 cells and performed integrated RNA sequencing (RNA-seq), Co-immunoprecipitation (Co-IP) coupled with mass spectrometry (M...

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Literature Corpus work: f6e2534b-68d6-5799-8994-87aa17166756
DOI: 10.64898/2026.08.24.746665

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