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Blocking the alternative sigma factor RpoN reduces virulence of <i>Pseudomonas aeruginosa</i> isolated from cystic fibrosis patients and increases antibiotic sensitivity in a laboratory strain

2018-06-06

Abstract excerpt

Multidrug-resistant organisms (MDROs) are increasing in the health care setting, and there are few antimicrobial agents available to treat infections caused by these bacteria. Pseudomonas aeruginosa is an opportunistic pathogen in burn patients and individuals with cystic fibrosis (CF), and a leading cause of nosocomial infections. P. aeruginosa is inherently resistant to many antibiotics and can develop or acqu...

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Literature Corpus work
1854b382-25db-5adc-8641-c7373120fb93
DOI
10.1101/340307
Open publication

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Blocking the alternative sigma factor RpoN reduces virulence of <i>Pseudomonas aeruginosa</i> isolated from cystic fibrosis patients and increases antibiotic sensitivity in a laboratory strainDOI 10.1101/340307
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