Article

Small molecules with antibiofilm, antivirulence and antibiotic synergy activities against <i>Pseudomonas aeruginosa</i>

2016-08-01

Abstract excerpt

Biofilm formation is a universal bacterial strategy for long-term survival in nature and during infections. Biofilms are dense microbial communities enmeshed within a polymeric extracellular matrix that protects bacteria from antibiotic exposure and the immune system and thus contribute to chronic infections. Pseudomonas aeruginosa is an archetypal biofilm-forming organism that utilizes a biofilm growth strategy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d4096ee-98ea-5ecf-bad3-3bbc70022a3c
DOI: 10.1101/067074

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Small molecules with antibiofilm, antivirulence and antibiotic synergy activities against <i>Pseudomonas aeruginosa</i>DOI 10.1101/067074Read

<i>Pseudomonas aeruginosa</i> increases the sensitivity of biofilm-grown <i>Staphylococcus aureus</i> to membrane-targeting antiseptics and antibioticsSemantic proximity Read

Deciphering the molecular mechanisms underlying anti-pathogenic potential of a polyherbal formulation Enteropan <sup>®</sup> against multi-drug resistant <i>Pseudomonas aeruginosa</i>Semantic proximity Read

Targeting Quorum Sensing in Pseudomonas Aeruginosa Biofilms: Current and Emerging InhibitorsSemantic proximity Read

Small Molecules That Modulate Quorum Sensing and Control Virulence in<i>Pseudomonas aeruginosa</i>Semantic proximity Read

Engineering Microbial Physiology with Synthetic Polymers: Cationic Polymers Induce Biofilm Formation in <i>Vibrio cholerae</i> and Downregulate the Expression of Virulence GenesSemantic proximity Read

Efficacy of a phage cocktail preparation for chronic lung infection with <i>Pseudomonas aeruginosa</i> in miceSemantic proximity Read

Two unrelated Pseudomonas aeruginosa phages require the exopolysaccharide Psl for infectionSemantic proximity Read

A genetic screen identifies a role for <i>oprF</i> in <i>Pseudomonas aeruginosa</i> biofilm stimulation by subinhibitory antibioticsSemantic proximity Read

Bacteriophage treatment of <i>Pseudomonas aeruginosa</i> PA14 infection does not alter the native microbiome of <i>Caenorhabditis elegans</i>Semantic proximity Read

Antimicrobial resistance in biofilms: Exploring marine actinobacteria as a potential source of antibiotics and biofilm inhibitorsSemantic proximity Read

<i>Pseudomonas aeruginosa</i> PA5oct jumbo phage impacts planktonic and biofilm population and reduces its host virulenceSemantic proximity Read

Selective inhibition of the amyloid matrix of <i>Escherichia coli</i> biofilms by a bifunctional microbial metaboliteSemantic proximity Read