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Deletion of σ 54 ( rpoN ) Alters the Rate of Autolysis and Biofilm Formation in Enterococcus faecalis

12 Nov 2011

Abstract excerpt

Transcription initiation is a critical step in bacterial gene regulation and is often controlled by transcription regulators. The alternate sigma factor (σ(54)) is one such regulator that facilitates activator-dependent transcription initiation and thus modulates the expression of a variety of genes involved in metabolism and pathogenesis in bacteria. This study describes the role of σ(54) in the nosocomial...

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PMID: 22081387
DOI: 10.1128/jb.06046-11

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