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Article

Dual regulation of mucoidy in <i>Pseudomonas aeruginosa</i> and sigma factor antagonism

1 Apr 2000

Abstract excerpt

The conversion to mucoid, exopolysaccharide alginate-overproducing phenotype in Pseudomonas aeruginosa during chronic respiratory infections in cystic fibrosis patients occurs via mutations that activate the alternative sigma factor AlgU (sigmaE). In this study, we demonstrate that conversion to mucoidy can be caused via a second, algU-independent pathway, in which alginate production and transcription of the...

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PMID: 10792721
DOI: 10.1046/j.1365-2958.2000.01846.x

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Dual regulation of mucoidy in <i>Pseudomonas aeruginosa</i> and sigma factor antagonismPMID 10792721Read ↗

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