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A genetic screen identifies a role for <i>oprF</i> in <i>Pseudomonas aeruginosa</i> biofilm stimulation by subinhibitory antibiotics

2023-09-05

Abstract excerpt

Biofilms are surface-associated communities of bacteria that grow in a self-produced matrix of polysaccharides, proteins, and extracellular DNA (eDNA). Sub-minimal inhibitory concentrations (sub-MIC) of antibiotics induce biofilm formation, indicating a potential defensive response to antibiotic stress. However, the mechanisms behind sub-MIC antibiotic-induced biofilm formation are unclear. We show that treatment...

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Literature Corpus work
98256368-ec64-5ae9-b914-452338e7d5d4
DOI
10.1101/2023.09.05.556382
Open publication

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A genetic screen identifies a role for <i>oprF</i> in <i>Pseudomonas aeruginosa</i> biofilm stimulation by subinhibitory antibioticsDOI 10.1101/2023.09.05.556382
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