Article

Adjustment for index event bias in genome-wide association studies of subsequent events

2018-10-11

Abstract excerpt

Following numerous genome-wide association studies of disease susceptibility, there is increasing interest in genetic associations with prognosis, survival or other subsequent events. Such associations are vulnerable to index event bias, by which selection of subjects according to disease status creates biased associations if common causes of incidence and prognosis are not accounted for. We propose an adjustment...

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Literature Corpus work: 1822b45f-b181-5193-a955-63d381a4e0c0
DOI: 10.1101/436063

Open publication

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