Adjustment for index event bias in genome-wide association studies of subsequent events

Abstract excerpt

Following numerous genome-wide association studies of disease susceptibility, there is increasing interest in genetic associations with prognosis, survival or other subsequent events. Such associations are vulnerable to index event bias, by which selection of subjects according to disease status creates biased associations if common causes of incidence and prognosis are not accounted for. We propose an adjustment...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Associations and Epidemiology
• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to Liver Disease Diagnosis and Treatment