Article
Genetic risk of osteoarthritis operates during human fetal development
2022-09-15
Abstract excerpt
<title>Abstract</title> <p>Osteoarthritis (OA) is a polygenic disease of older people resulting in the breakdown of cartilage within articular joints. Although a leading cause of disability, there are no disease-modifying therapies. Evidence is emerging to support the origins of OA in skeletogenesis. Whilst methylation QTLs (mQTLs) co-localizing with OA GWAS signals have been identified in aged human cartilage an...
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Identifiers and source
- Literature Corpus work
- 17f85dc8-d176-5221-8ed6-4e2171aeaba1
- DOI
- 10.21203/rs.3.rs-2056256/v1