Article

Single-cell transcriptomics reveals immune response of intestinal cell types to viral infection

2020-08-19

Abstract excerpt

Human intestinal epithelial cells form a primary barrier protecting us from pathogens, yet only limited knowledge is available about individual contribution of each cell type to mounting an immune response against infection. Here, we developed a pipeline combining single-cell RNA-Seq and highly-multiplex RNA imaging and applied it to human intestinal organoids infected with human astrovirus, a model human enteric...

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Literature Corpus work: 3af4bba6-5162-57ca-a690-a4bcbe102009
DOI: 10.1101/2020.08.19.255893

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