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FinaleToolkit: Accelerating Cell-Free DNA Fragmentation Analysis with a High-Speed Computational Toolkit

2024-06-02

Abstract excerpt

<h4>Motivation</h4> Cell-free DNA (cfDNA) fragmentation pattern represents a promising non-invasive biomarker for disease diagnosis and prognosis. Numerous fragmentation features, such as end motif and window protection score (WPS), have been characterized in cfDNA genomic sequencing. However, the analytical tools developed in these studies are often not released to the liquid biopsy community or are inefficient...

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Literature Corpus work: 187f56a5-6789-50e7-8ffd-4e953b2ebbfb
DOI: 10.1101/2024.05.29.596414

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