Article

Exposure to the oral host niche yields rapid phenotypic and genotypic diversification in <i>Candida albicans</i>

2018-01-25

Abstract excerpt

In vitro studies suggest that stress may generate random standing variation, and that different cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been tested with pathogenic fungi growing within their host niche in vivo . Here, we analyzed the generation of both genotypic and phenotypic diversity during exposure of Candida albicans to the mouse oral cavity. Ploidy, aneuploidy...

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Identifiers and source

Literature Corpus work: 17c52422-b56e-58ee-93a1-cc8350145f32
DOI: 10.1101/254201

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