Article

A rapid and dynamic role for FMRP in the plasticity of adult neurons

2023-09-03

Abstract excerpt

Fragile X syndrome (FXS) is a neuro-developmental disorder caused by silencing Fmr1 , which encodes the RNA-binding protein FMRP. Although Fmr1 is expressed in adult neurons, it has been challenging to separate acute from chronic effects of loss of Fmr1 in models of FXS. We have used the precision of Drosophila genetics to test if Fmr1 acutely affects adult neuronal plasticity in vivo , focusing on the s-LNv...

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Literature Corpus work: 17c1a5ba-3f81-5f51-a002-af5382d2eae8
DOI: 10.1101/2023.09.01.555985

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