Article
Fragile X protein controls neural stem cell proliferation in the Drosophila brain.
Human molecular genetics - 1 Aug 2010
Callan Matthew A, Cabernard Clemens, Heck Jennifer, Luois Samantha, Doe Chris Q, Zarnescu Daniela C
Abstract excerpt
Fragile X syndrome (FXS) is the most common form of inherited mental retardation and is caused by the loss of function for Fragile X protein (FMRP), an RNA-binding protein thought to regulate synaptic plasticity by controlling the localization and translation of specific mRNAs. We have recently shown that FMRP is required to control the proliferation of the germline in Drosophila. To determine whether FMRP is...
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