Article

Alternative Polyadenylation Determines the Functional Landscape of Inverted Alu Repeats

2023-11-30

Abstract excerpt

<h4>Summary</h4> Inverted Alu repeats (IRAlus) are abundantly found in the transcriptome, especially in introns and 3′ UTRs. Yet, the biological significance of 3′ UTR IRAlus remains largely unknown. Here, we find that IRAlus induce the silencing of genes involved in essential signaling pathways. We utilize J2 antibody to directly capture and map the double-stranded RNA structure of 3′ UTR IRAlus in the transcrip...

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Literature Corpus work: 1779f689-c37f-5bb9-90fb-141cf868dca9
DOI: 10.1101/2023.11.30.569399

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