Article

Investigation of cell mechanics and migration on DDR2-expressing neuroblastoma cell line

2024-08-16

Abstract excerpt

Neuroblastoma is a devastating disease accounting for ~15% of all childhood cancer deaths. Collagen content and fiber association within the tumor stroma influence tumor progression and metastasis. High expression levels of collagen receptor kinase, Discoidin domain receptor II (DDR2), are associated with poor survival of neuroblastoma patients. Additionally, cancer cells generate and sustain mechanical forces wit...

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Identifiers and source

Literature Corpus work: 17706c83-1650-5f63-8498-f1fc41212bf0
DOI: 10.1101/2024.08.15.607761

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