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Article

The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA.

Journal of cell science - 15 May 2009

Huang Yun, Arora Pamela, McCulloch Christopher A, Vogel Wolfgang F

Abstract excerpt

The spreading and migration of cells on adhesive substrates is regulated by the counterbalance of contractile and protrusive forces. Non-muscle myosin IIA, an ubiquitously expressed contractile protein and enzyme, is implicated in the regulation of cell spreading and directional migration in response to various stimuli. Here we show that discoidin domain receptor 1 (DDR1), a tyrosine kinase receptor activated by...

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Share to Actin Cytoskeleton
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Share to Collagen Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterocyclic Compounds, 4 or More Rings

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Source

Identifiers

PMID: 19401332
DOI: 10.1242/jcs.046219

Genes

DDR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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