Article

Mechanical confinement and DDR1 signalling synergise to regulate collagen-induced apoptosis in rhabdomyosarcoma cells

2022-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Fibrillar collagens promote cell proliferation, migration, and survival in various epithelial cancers and are generally associated with tumour aggressiveness. However, the impact of fibrillar collagens on soft tissue sarcoma behaviour remains poorly understood. Unexpectedly, we find here that fibrillar collagen-related gene expression is associated with favourable patient prognosis in rhabdomyos...

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Literature Corpus work: 8a7af845-8f71-5d53-832c-2dd6e858651a
DOI: 10.1101/2022.04.26.489526

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