Article

Promoter activity-based case-control association study on <i>SLC6A4</i> highlighting hypermethylation and altered amygdala volume in male patients with schizophrenia

2020-05-08

Abstract excerpt

Associations between altered DNA methylation of the serotonin transporter (5-HTT)-encoding gene SLC6A4 and early life adversity, mood and anxiety disorders, and amygdala reactivity have been reported. However, few studies have examined epigenetic alterations of SLC6A4 in schizophrenia (SZ). We examined CpG sites of SLC6A4 , whose DNA methylation levels have been reported to be altered in bipolar disorder, using...

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Literature Corpus work: 1768ffb1-f315-5192-a23c-9bd1be6e9b59
DOI: 10.1101/2020.05.06.058792

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